Hyper Lode Runner doesn't keep the high score after the Game Boy is turned off. With this patch the high score will be saved.
You will also need to use the "Hyper Lode Runner Highscore Save.sav" file found in the zip file.
Database match: Hyper Lode Runner (World) (Rev A)
Database: No-Intro: Game Boy/Color (v. 20180815-131105)
File/ROM SHA-1: 261DA795C7B4155F1B8083ACC55DA78699C8A0DE
File/ROM CRC32: B3A86164