Madden NFL 2001 for Nintendo 64 features various customizable modes, allowing players to create plays and players, manage a franchise, and collect Madden Cards. These cards enhance gameplay by enabling options such as adding fifth downs or restricting CPU teams to third downs. They also modify player ratings and unlock special stadiums and Hall of Fame and All-Madden teams.
Madden NFL 2001 includes several customizable modes. Players have the ability to create a play, create a player, run a franchise, and collect Madden Cards, allowing players to perform certain actions during gameplay (for example, adding 5th downs, or limiting the CPU-controlled team to 3rd downs). The cards can also alter individual player ratings, unlock special stadiums, and unlock Hall of Fame and All-Madden teams.