G.I. Joe: The Rise of Cobra is an action-adventure game for the Nintendo DS released in conjunction with the film of the same name. Players control Duke, Scarlett, and other members of the G.I. Joe team as they rescue captured allies and battle the evil organization Cobra. Set across various locations, players must thwart Cobra's plans and confront key adversaries, culminating in a final showdown at the North Magnetic Pole.
After the events of the film, Duke and Scarlett travels to the Arctic and free Heavy Duty, Ripcord and Snake Eyes from the M.A.R.S Detention Center. Also, they fight the Baroness and bring her to the Pit. In Egypt, the Joes learn that Cobra is taking the Apep (Gem), and must defeat Firefly. In the jungle, the Joes learn that Cobra is making a pyramid-like building in the middle of the jungle. From there, the Joes must defeat James McCullen (who now takes the identity of Destro) at the rooftop of the pyramid building. Finally, they must defeat the Cobra Commander and Storm Shadow at North Magnetic Pole Volcano base.