Cho Aniki: Seinaru Protein Densetsu is a side-scrolling shooter for the PlayStation 2. Set in the mythical Holy Land, the game revolves around characters Adon and Samson, who must defend a powerful protein from an evil architect. Players navigate vibrant levels filled with eccentric enemies, aiming to preserve the legendary substance said to create the ultimate physique.
Located in the "Holy Land," there exists protein which the legend says that when ingested, it can sculpt the ultimate body. The protein appeared in front of Adon and Samson, asking for protection as it is targeted by the evil builder. Adon and Samson head to the Holy Land to rid the evil from the land and protect the protein.