Genocide 2 is a Super Nintendo action game set in the year 228. Players control bionic soldier Jeff Hazard, who pilots a powerful robot to confront the rogue mecha Goliath, a sophisticated fighter unit. Tasked by CONEX corporation, Hazard embarks on a mission to investigate the threat posed by a mysterious weapon being developed by the corporation, battling through various challenges.
In 228, the rogue unit Tracer Type 184 (codenamed Goliath), a highly sophisticated fighter mecha protects the city from evil. The CONEX corporation is developing an unknown weapon and the bionic soldier Jeff Hazard, on board of his powerful robot-warrior, is sent to investigate the situation.